One-Pot Syntheses of 6-Mercaptopurines (6MP) from 4,5-Diamino-6-chloro-pyrimidines.
โ Scribed by Sagun Tandel; Igor Bliznets; Katalin Ebinger; You-An Ma; Dilip Bhumralkar; Mohan Thiruvazhi
- Publisher
- John Wiley and Sons
- Year
- 2004
- Weight
- 82 KB
- Volume
- 35
- Category
- Article
- ISSN
- 0931-7597
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## Abstract The reaction of 1โarylโ3โ(dimethylamino)โ1โpropanones 1 with one equivalent of 4,5โdiaminoโ1__H__โpyrimidinโ6โones 2, in acidic medium, leads to the formation of 4โarylโ2,3,6,7โtetrahydroโ1__H__โpyrimido[4,5โ__b__]โ[1,4]diazepinโ6โones 3. The structure elucidation of the products is bas