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ChemInform Abstract: Synthesis of 4-Aryl-2,3,6,7-tetrahydro-1H-pyrimido[4,5-b][1,4]diazepin-6-ones from 4,5-Diamino-1H-pyrimidin-6-ones and 1-Aryl-3-(dimethylamino)-1-propanones.

โœ Scribed by Braulio Insuasty; Juan Carlos Argoti; Samuel Gomez; Jairo Quiroga; Roberto Martinez; Enrique Angeles; Ruben Gabino; Manuel Nogueras; Adolfo Sanchez

Publisher
John Wiley and Sons
Year
2010
Weight
32 KB
Volume
30
Category
Article
ISSN
0931-7597

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ChemInform Abstract: Facile Synthesis of
ChemInform Abstract: Facile Synthesis of 6-Aryl-1,3-dimethyl-5H-pyrimido[4,5-b][1,4]diazepine-2,4(1H,3H)-diones.
โœ Shahriyar Taghavi-Moghadam; Ruediger Stumpf; Helmut Fischer; Wolfgang Pfleiderer ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› John Wiley and Sons โš– 32 KB

## Facile Synthesis of 6-Aryl-1,3-dimethyl-5H-pyrimido[4,5b][1,4]diazepine-2,4(1H,3H)-diones. -A new approach to the regioselective synthesis of the title compounds (IV) starting from readily accessible 6-amino-5-benzylideneaminopyrimidines (I) is described. Condensation of compound (I) with diet