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Design, Synthesis and Diuretic Activity of Some Novel 2,4-Diamino-6-aryl-7-arylaminopyrimido[4,5-d]pyrimidin-5-(6H)-ones.

✍ Scribed by Ishwarsinh Rathod; Mahesh T. Chhabria; Atul S. Chaudhari; Mitesh H. Jani


Publisher
John Wiley and Sons
Year
2006
Weight
15 KB
Volume
37
Category
Article
ISSN
0931-7597

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✦ Synopsis


Abstract

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Synthesis of 4-aryl-2,3,6,7-tetrahydro-1
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## Abstract The reaction of 1‐aryl‐3‐(dimethylamino)‐1‐propanones 1 with one equivalent of 4,5‐diamino‐1__H__‐pyrimidin‐6‐ones 2, in acidic medium, leads to the formation of 4‐aryl‐2,3,6,7‐tetrahydro‐1__H__‐pyrimido[4,5‐__b__]‐[1,4]diazepin‐6‐ones 3. The structure elucidation of the products is bas