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Oncornavirus-like particles in HeLa cells. III. Biochemical characterization of the virus

✍ Scribed by Kenneth F. Watson; Karin Mölling; Hans Gelderblom; Heinz Bauer

Publisher
John Wiley and Sons
Year
1974
Tongue
French
Weight
419 KB
Volume
13
Category
Article
ISSN
0020-7136

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✦ Synopsis

Abstract

Oncornavirus‐like particles observed and purified from HeLa cell culture supernates have a density in sucrose of 1.16‐1.17 g/cm^3^. They contain DNA polymerase and ribonuclease activities with properties characteristic of reverse transcriptase and ribonuclease H of known oncornaviruses. The DNA polymerase and RNase H are antigenically similar to those of Mason‐Pfizer monkey virus.

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