Epstein-Barr virus (EBV)-encoded RNAs (EBERs) are the most abundant viral transcripts in latently EBV-infected cells. Recently, we found that EBERs play a key role in the maintenance of malignant phenotypes of Burkitt's lymphoma (BL) cells. They confer clonability in soft agarose, tumorigenicity in
Oncogenic role of Epstein-Barr virus-encoded small RNAs (EBERs) in nasopharyngeal carcinoma
✍ Scribed by Tomokazu Yoshizaki; Kazuhira Endo; Qingchun Ren; Naohiro Wakisaka; Shigeyuki Murono; Satoru Kondo; Hiroshi Sato; Mitsuru Furukawa
- Book ID
- 116223377
- Publisher
- Elsevier Science
- Year
- 2007
- Tongue
- English
- Weight
- 273 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0385-8146
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The authors thank Drs. Anthony J. Janckila and Lung T. Yam of the University of Louisville, Louisville, Kentucky, for their criticism of this article. They also would like to thank Miss Su-Huei Lee for her excellent technique for in situ hybridization and immunohistochemical stainings.
## Abstract It has been generally believed that the Epstein–Barr virus (EBV)‐encoded small RNA 1 and 2 (EBER1 and EBER2) genes are conserved as two families that correlated with type 1 (B95‐8) and type 2 (AG876 or P3HR‐1) EBV strains. EBER polymorphism and its association with EBV‐associated diseas