We have previously shown that high levels of antibody to Epstein-Barr virus (EBV)-specific DNase may be a useful marker for the early diagnosis of nasopharyngeal carcinoma (NPC). Sera from 3,368 males in an area with a high risk for the development of NPC were examined for the presence of antibody t
Expression of Epstein-Barr virus-encoded RNAs as a marker for metastatic undifferentiated nasopharyngeal carcinoma
β Scribed by Tsu-Yi Chao; Kuan-Chi Chow; Jang-Yang Chang; Chang-Chung Wang; Tang-Yi Tsao; Horng-Jyh Harn; Kwan-Hwa Chi
- Publisher
- John Wiley and Sons
- Year
- 1996
- Tongue
- English
- Weight
- 620 KB
- Volume
- 78
- Category
- Article
- ISSN
- 0008-543X
No coin nor oath required. For personal study only.
β¦ Synopsis
The authors thank Drs. Anthony J. Janckila and Lung T. Yam of the University of Louisville, Louisville, Kentucky, for their criticism of this article. They also would like to thank Miss Su-Huei Lee for her excellent technique for in situ hybridization and immunohistochemical stainings.
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## Abstract EpsteinβBarr virus (EBV) is present within the tumor cells of most cases of nasopharyngeal carcinoma (NPC). Recent studies suggest that tumor burden is proportional to the level of EBV DNA in blood and that rapid blood testing can be used to guide therapeutic intervention. The relative