## RESULTS. In specimens from 107 patients with NPC, EBV was detected by PCR in 2 Department of Pathology, the Johns Hopkins 97 cases (90.7%) and by EBER in situ hybridization in 105 cases (98.1%). In speci-
Evaluation of multiple antibodies to Epstein-Barr virus as markers for detecting patients with nasopharyngeal carcinoma
β Scribed by Liu, Mei-Ying; Chang, Yen-Liang; Ma, Jeng; Yang, Huey-Lang; Hsu, Mow-Ming; Chen, Chien-Jen; Chen, Jen-Yang; Yang, Czau-Siung
- Publisher
- John Wiley and Sons
- Year
- 1997
- Tongue
- English
- Weight
- 191 KB
- Volume
- 52
- Category
- Article
- ISSN
- 0146-6615
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Epstein-Barr virus (EBV)-associated nasopharyngeal carcinoma (NPC) generally occurs in adults, especially in high-prevalence populations such as the Chinese and Eskimos. In Maghrebian populations, young patients affected with this malignancy represent 25% of the total NPC cases. In adults with NPC,
The Epstein-Barr virus (EBV) open reading frame BHRF1, a homologue of the oncogene bcl-2, was cloned from a patient with nasopharyngeal carcinoma (NPC) and overexpressed in Escherichia coli. The resulting recombinant BHRF1 fusion protein, with an apparent molecular weight of 35 KD, was used as antig