On the stability of S-(alkylsulfanyl) cysteine derivatives during solid-phase synthesis
β Scribed by B. H. Rietman; R. F. R. Peters; G. I. Tesser
- Publisher
- Elsevier Science
- Year
- 2010
- Tongue
- English
- Weight
- 521 KB
- Volume
- 114
- Category
- Article
- ISSN
- 0165-0513
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π SIMILAR VOLUMES
Phosphonium derivatives of HOAt such as PyAOP are useful for the solid-phase preparation of a range of peptides that include those incorporating hindered amino acids, difficult short sequences, and cyclic peptides. An advantage relative to uronium salts is that excess PyAOP does not undergo the detr
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## Abstract Aliphatic aldehydes were synthesized on a solid support and subjected to an enantioselectively catalyzed oxaβDielsβAlder reaction with Danishefskyβs diene. Employing 5 molβ% of a Cr(III)βsalen catalyst enantiomeric ratios up to>99β% and yields up to 40β% over five steps were achieved. F
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