A maximum likelihood estimate of the sex
โ
R. M. Winter; E. G. D. Tuddenham; E. Goldman; K. B. Matthews
๐
Article
๐
1983
๐
Springer
๐
English
โ 314 KB
Carrier detection tests were carried out on 21 mothers of isolated cases of severe Haemophilia A, according to WHO recommendations. A maximum likelihood estimate of the male to female mutation ratio of 9.6 (95% confidence limits 2.2-41.5) was obtained.