๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

ESTIMATES OF THE SEX RATIO OF MUTATION RATES IN SEX-LINKED CONDITIONS BY THE METHOD OF MAXIMUM LIKELIHOOD

โœ Scribed by C. A. B. SMITH; S. J. KILPATRICK


Book ID
115246721
Publisher
John Wiley and Sons
Year
1958
Tongue
English
Weight
305 KB
Volume
22
Category
Article
ISSN
0003-4800

No coin nor oath required. For personal study only.


๐Ÿ“œ SIMILAR VOLUMES


A maximum likelihood estimate of the sex
โœ R. M. Winter; E. G. D. Tuddenham; E. Goldman; K. B. Matthews ๐Ÿ“‚ Article ๐Ÿ“… 1983 ๐Ÿ› Springer ๐ŸŒ English โš– 314 KB

Carrier detection tests were carried out on 21 mothers of isolated cases of severe Haemophilia A, according to WHO recommendations. A maximum likelihood estimate of the male to female mutation ratio of 9.6 (95% confidence limits 2.2-41.5) was obtained.

Direct estimate of the haemophilia B (fa
โœ A. J. Montandon; P. M. Green; D. R. Bentley; R. Ljung; S. Kling; I. M. Nilsson; ๐Ÿ“‚ Article ๐Ÿ“… 1992 ๐Ÿ› Springer ๐ŸŒ English โš– 494 KB

Mutation rates for X-linked recessive diseases have so far been estimated indirectly by postulating an equilibrium between the loss of defective genes caused by the low reproductive fitness of affected males and the gain resulting from new mutations. Here, for the first time, we directly estimate bo