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A maximum likelihood estimate of the sex ratio of mutation rates in Haemophilia A

✍ Scribed by R. M. Winter; E. G. D. Tuddenham; E. Goldman; K. B. Matthews

Publisher
Springer
Year
1983
Tongue
English
Weight
314 KB
Volume
64
Category
Article
ISSN
0340-6717

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✦ Synopsis

Carrier detection tests were carried out on 21 mothers of isolated cases of severe Haemophilia A, according to WHO recommendations. A maximum likelihood estimate of the male to female mutation ratio of 9.6 (95% confidence limits 2.2-41.5) was obtained.

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