Mutation Rates in Humans. I. Overall and Sex-Specific Rates Obtained from a Population Study of Hemophilia B
β Scribed by P.M. Green; S. Saad; C.M. Lewis; F. Giannelli
- Book ID
- 117853067
- Publisher
- American Society of Human Genetics
- Year
- 1999
- Tongue
- English
- Weight
- 99 KB
- Volume
- 65
- Category
- Article
- ISSN
- 0002-9297
- DOI
- 10.1086/302651
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Mutation rates for X-linked recessive diseases have so far been estimated indirectly by postulating an equilibrium between the loss of defective genes caused by the low reproductive fitness of affected males and the gain resulting from new mutations. Here, for the first time, we directly estimate bo
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