On-line synthesis of [11C]cyanide from cyclotron-produced [11C]carbon dioxide
β Scribed by Toshihiko Hara; Masaaki Iio
- Publisher
- Elsevier Science
- Year
- 1987
- Weight
- 187 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0883-2889
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π SIMILAR VOLUMES
Radiolabeled chlorpromazine was prepared by carboxylation of the N-trimethylsilyl derivative of norchlorpromazine with [11C]carbon dioxide, followed by in situ lithium aluminum hydride reduction. Radiochemical yields of 22-24% and radiochemical purities in the range of 93-98% were achieved.
A method for the preparation of [1-11C]D-glucose (III) and [1-11C] D-mannose (IV) from [11C] nitromethane is described. [11C]Nitromethane was produced using the on-line method from [11C]methyl iodide. The condensation of no-carrier-added or carrier-added [11C]nitromethane with D-arabinose to form th
## Abstract The synthesis of the ^11^Cβlabelled bifunctional precursors 3β[^11^C]cyanoethyltriphenylphosphonium bromide (1β²), 4β[^11^C]cyanopropyltriphenylphosphonium bromide (2β²), 5β[^11^C]cyanobutyltriphenylphosphonium bromide (3β²), 4β[^11^C]cyanobutyltriphenylphosphonium iodide (4β²) and 5β[^11^C