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Ocular responses to superoxide generated by intraocular injection of xanthine oxidase

✍ Scribed by T.W. Mittag; B.R. Hammond; K.E. Eakins; P. Bhattacherjee

Book ID
115893862
Publisher
Elsevier Science
Year
1985
Tongue
English
Weight
683 KB
Volume
40
Category
Article
ISSN
0014-4835

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Bovine brain endothelial cells (EC) that were isolated and propagated in pure culture had increased (> 20-fold) levels of xanthine oxidase and xanthine dehydrogenase activity compared to whole brain homogenate. Brain EC also released superoxide anion (0;) into the extracellular medium. Treatment of