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OC.07.4 THE ROLE OF SMOOTH MUSCLE IN CROHN'S DISEASE INTESTINAL FIBROSIS

✍ Scribed by Scirocco, A.; Rosati, S.; Sferra, R.; Vetusti, A.; Pallotta, N.; Tellan, G.; Pronio, A.; Corazziari, E.S.; Severi, C.


Book ID
123237362
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
242 KB
Volume
45
Category
Article
ISSN
1590-8658

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Background: Stricture formation occurs in %30% of patients with Crohn's disease (CD) and is a significant cause of morbidity. Strictures are characterized by intestinal smooth muscle cell hyperplasia, smooth muscle cell hypertrophy, and fibrosis due to excess net extracellular matrix production, inc