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The role of interleukin 17 in Crohn’s disease-associated intestinal fibrosis

✍ Scribed by Biancheri, Paolo; Pender, Sylvia LF; Ammoscato, Francesca; Giuffrida, Paolo; Sampietro, Gianluca; Ardizzone, Sandro; Ghanbari, Amir; Curciarello, Renata; Pasini, Alessandra; Monteleone, Giovanni; Corazza, Gino R; MacDonald, Thomas T; Di Sabatino, Antonio

Book ID
121630949
Publisher
BioMed Central
Year
2013
Tongue
English
Weight
849 KB
Volume
6
Category
Article
ISSN
1755-1536

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Background: Glucocorticoids and monoclonal antibodies to tumor necrosis factor reduce inflammation in Crohn's disease (CD). Rapid luminal healing, however, may promote intestinal stricture formation. The aim of this study was to examine fibrosis-associated gene expression in the intestine of patient