✦ LIBER ✦

Numerical analysis of thermal denaturation of nucleic acids

✍ Scribed by J. Gabarro

Publisher: Elsevier Science
Year: 1978
Tongue: English
Weight: 627 KB
Volume: 91
Category: Article
ISSN: 0003-2697
DOI: 10.1016/0003-2697(78)90845-x

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✦ Synopsis

Denaturation of DNA molecules by stepwise incrementation of the temperature leads to melting profiles showing a fine structure, composed of individual melting modes. A method is described by which quantitative physical information brought by the modes can be extracted from the melting profile. Related problems such as data editing and smoothing are also discussed.

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