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Nucleoside 5′-triphosphates with modified sugars as substrates for DNA polymerases

✍ Scribed by Zurab G. Chidgeavadze; Robert Sh. Beabealashvilli; Alexander A. Krayevsky; Marina K. Kukhanova


Book ID
119119450
Publisher
Elsevier Science
Year
1986
Tongue
English
Weight
926 KB
Volume
868
Category
Article
ISSN
0167-4781

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DNA polymerase enzymes process their natural substrates with very high specificity. Yet recent experiments have shown that these enzymes can also process DNA in which the backbone or bases are modified to a surprising degree. Such experiments have important implications in understanding the mechanis