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Nucleophilic Addition of Enols and Enamines to α,β-Unsaturated Acyl Azoliums: Mechanistic Studies

✍ Scribed by Ramesh C. Samanta; Biplab Maji; Dr. Suman De Sarkar; Dr. Klaus Bergander; Dr. Roland Fröhlich; Dr. Christian Mück-Lichtenfeld; Prof. Dr. Herbert Mayr; Prof. Dr. Armido Studer


Book ID
112000759
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
623 KB
Volume
51
Category
Article
ISSN
0044-8249

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Diastereoselective michael addition of n
✍ Jacek G. Sośnicki; Tadeusz S. Jagodziński; Jürgen Liebscher 📂 Article 📅 1997 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 427 KB

## Abstract 5,6‐Dihydropyridine‐2‐thiones 2 are synthesized from 5,6‐dihydropyridin‐2‐ones 1 and Lawesson reagent. Stereoselective Michael‐like addition of amines, methylhydrazine or functionalized thiols affords __trans__ piperidine‐2‐thiones 5 with the corresponding heterosubstituent in position