C-acylation of enolates from lithium dimethylcuprate addition to α,β-unsaturated ketones
✍ Scribed by S. Bernasconi; P. Gariboldi; G. Jommi; M. Sisti
- Publisher
- Elsevier Science
- Year
- 1980
- Tongue
- French
- Weight
- 227 KB
- Volume
- 21
- Category
- Article
- ISSN
- 0040-4039
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Preformed lithium enolates of ketones react with acyclic a,p-unsaturated ketones to give 1,5-diketones in good chemical yields. A strong correlation exists between enolate geometry and product stereochemistry; enolates having the z configuration provide anti addition products while E enolates usua