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Conjugate addition to α,β-unsaturated ketones with mixed lithium triorganozincates

✍ Scribed by Randall A. Watson; Richard A. Kjonaas


Publisher
Elsevier Science
Year
1986
Tongue
French
Weight
232 KB
Volume
27
Category
Article
ISSN
0040-4039

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1,4-Addition of triorganozincates and si
✍ Tückmantel, Werner ;Oshima, Koichiro ;Nozaki, Hitosi 📂 Article 📅 1986 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 683 KB

Lithium and magnesium triorganozincates, prepared by combination of ZnC12(TMEDA) with 3 molar equivalents of RLi or RMgX, or from dialkylzinc and 1 molar equivalent of RLi or RMgX, react with 2-cyclohexen-1-one (1) under mild conditions to produce moderate to good yields of the 1 &addition products