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Novel types of mutation identified at the hprt locus of human T-lymphocytes

✍ Scribed by Sai-Mei Hou


Book ID
113194617
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
684 KB
Volume
308
Category
Article
ISSN
0027-5107

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Splicing mutations at the HPRT locus in
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We studied 58 splicing mutations originating in observed. The predicted change in three of the base vivo at the hypoxanthine guanine phosphoribosyl-substitutions would be a stop codon. The tandem transferase (HPRT) locus in T-cells of 30 nonsmoking mutation (CC r TT) occurred at position 550-551, ma