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Hydrogen peroxide induced mutations at the HPRT locus in primary human T-lymphocytes

✍ Scribed by Silvia Dı́az-Llera; Andrej Podlutsky; Anne-May Österholm; Sai-Mei Hou; Bo Lambert


Book ID
117766571
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
117 KB
Volume
469
Category
Article
ISSN
1383-5718

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Splicing mutations at the HPRT locus in
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We studied 58 splicing mutations originating in observed. The predicted change in three of the base vivo at the hypoxanthine guanine phosphoribosyl-substitutions would be a stop codon. The tandem transferase (HPRT) locus in T-cells of 30 nonsmoking mutation (CC r TT) occurred at position 550-551, ma