Molecular analysis of styrene oxide-induced mutations at the HPRT locus in human T-lymphocytes
β Scribed by T. Bastlova; A. Podlutsky
- Book ID
- 114133249
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- English
- Weight
- 139 KB
- Volume
- 360
- Category
- Article
- ISSN
- 0165-1161
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We studied 58 splicing mutations originating in observed. The predicted change in three of the base vivo at the hypoxanthine guanine phosphoribosyl-substitutions would be a stop codon. The tandem transferase (HPRT) locus in T-cells of 30 nonsmoking mutation (CC r TT) occurred at position 550-551, ma
## Molecular analysis of hypoxanthine-guanine analyzed in more detail by sequencing the gephosphoribosyltransferase (hprt) cDNA from nomic regions flanking the mis-spliced exon. ## 6-thioguanine-resistant T-lymphocytes cloned Base pair substitutions or small deletions causfrom smoking and non-s