## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v
Novel Synthesis of (3R,4R)‐4‐Acetoxy‐3‐[1′(R)‐tert‐butyldimethylsilyloxyethyl] Azetidin‐2‐one: A Key Intermediate for Penem and Carbapenem Synthesis
✍ Scribed by Kumar Singh, Santosh; Singh, G. B.; Byri, V. K.; Satish, B.; Dhamjewar, Ravi; Gopalan, B.
- Book ID
- 126968224
- Publisher
- Taylor and Francis Group
- Year
- 2008
- Tongue
- English
- Weight
- 133 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0039-7911
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
A short stereoselective synthesis of the acetoxy azetidinone (1), an important precursor of several biologically active -lactam antibiotics, has been accomplished in seven steps and 32.8% overall yield from the easily available and inexpensive (R) ethyl 3-hydroxybutanoate.
Incorporation of a chiral ketone into the established tetrahydro-1,3-oxazine route to thienamycin analogues, has enabled the isolation of single enantiomers having the naturally occurring (&)-configuration at the bridgehead.
A Practical Synthesis of 3-[(1R)-1-t-Butyldimethylsilyloxyethyl]-4-[(2R)-4-halo-3-oxo-2-butyl]azetidinone, a Versatile Intermediate for Carbapenem Antibiotics. -The readily available carboxylic acid (I) is converted efficiently by a three-step procedure into the title compounds such as (VI). Desily