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Novel synthesis of 3,4-dihydro-1H-2,1,3-benzothiadiazine 2,2-dioxides

✍ Scribed by Pews, R. Garth

Book ID
127134901
Publisher
American Chemical Society
Year
1979
Tongue
English
Weight
394 KB
Volume
44
Category
Article
ISSN
0022-3263

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Facile synthesis of 4-substituted 3,4-di
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## Abstract A new method for the preparation of 4‐substituted 3,4‐dihydro‐1__H__‐2,1,3‐benzothiadiazine 2,2‐dioxides is described. Treatment of __t__‐butyl __N__‐phenylsulfamoylcarbamate derivatives (**1**) with different aldehydes afforded the corresponding intramolecular cyclized products **2** u

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A simple method for the preparation of 4,4-disubstituted-3,4-dihydro-1H-2,1,3-benzothiadiazine 2,2dioxides is described. Treatment of N-sulfonyl ketimines 2 and 3 with different carbon nucleophiles afforded the corresponding of 4,4-disubstituted-3,4-dihydro-1H-2,1,3-benzothiadiazine 2,2-dioxides 1 i