A straightforward synthesis of 4-substituted 3,4-dihydro-1H-2,1,3-benzothiadiazine 2,2-dioxides
✍ Scribed by Javier Agejas; Jose L Garcı́a-Navı́o; Carlos Lamas
- Publisher
- Elsevier Science
- Year
- 2000
- Tongue
- French
- Weight
- 87 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0040-4039
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## Abstract A new method for the preparation of 4‐substituted 3,4‐dihydro‐1__H__‐2,1,3‐benzothiadiazine 2,2‐dioxides is described. Treatment of __t__‐butyl __N__‐phenylsulfamoylcarbamate derivatives (**1**) with different aldehydes afforded the corresponding intramolecular cyclized products **2** u
A simple method for the preparation of 4,4-disubstituted-3,4-dihydro-1H-2,1,3-benzothiadiazine 2,2dioxides is described. Treatment of N-sulfonyl ketimines 2 and 3 with different carbon nucleophiles afforded the corresponding of 4,4-disubstituted-3,4-dihydro-1H-2,1,3-benzothiadiazine 2,2-dioxides 1 i
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