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Novel Synthesis and Antitumor Evaluation of Polyfunctionally Substituted Heterocyclic Compounds Derived from 2-Cyano-N-(3-cyano-4,5,6,7-tetrahydrobenzo[b]thiophen-2-yl)-acetamide

✍ Scribed by Shams, Hoda Z.; Mohareb, Rafat M.; Helal, Maher H.; Mahmoud, Amira E.


Book ID
118205294
Publisher
Molecular Diversity Preservation International
Year
2010
Tongue
English
Weight
219 KB
Volume
16
Category
Article
ISSN
1420-3049

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πŸ“œ SIMILAR VOLUMES


The reaction of 2-amino-3-cyano-4,5,6,7-
✍ Rafat M. Mohareb; Fatma A. El-Omran; Jonathan Z. Ho πŸ“‚ Article πŸ“… 2001 πŸ› John Wiley and Sons 🌐 English βš– 114 KB

## Abstract The reaction of 2‐amino‐3‐cyano‐4,5,6,7‐tetrahydrobenzo[b]thiophene (**1**) with diethyl malonate (**2**) gave two products: **3** and **4**. The reactivity of **3** toward a variety of chemical reagents was studied to give azoles, azines, and their fused derivatives. Β© 2001 John Wiley

Reaction of 2-amino-3-cyano-4,5,6,7-tetr
✍ Rafat M. Mohareb; Mona H. Mohamed πŸ“‚ Article πŸ“… 2001 πŸ› John Wiley and Sons 🌐 English βš– 223 KB

## Abstract The reaction of 2‐amino‐3‐cyano‐4,5,6,7‐tetrahydrobenzo[b]thiophene **1** with ethyl acetoacetate **2** gave compound **3**. The reactivity of the latter product toward a variety of chemical reagents was studied to give fused thiophene derivatives of potential pharmaceutical interest. Β©