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Novel sulfone-based thiophilic ligands for the high-performance liquid chromatographic purification of antibodies

✍ Scribed by Alexander Schwarz; Fortune Kohen; Meir Wilchek

Book ID
103958446
Publisher
Elsevier Science
Year
1994
Weight
650 KB
Volume
22
Category
Article
ISSN
0923-1137

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Thiophilic adsorption chromatography, developed originally by Porath and colleagues (1985, FEBS Lett. 185, 306-310) for conventional chromatographic techniques, was transformed to the HPLC mode upon preparation of new and improved sulfur-containing silica beads. The new thiophilic adsorbent is of hi