A Method for the Purification of Oligonu
โ
M.B. Arghavani; L.J. Romano
๐
Article
๐
1995
๐
Elsevier Science
๐
English
โ 595 KB
Synthetic oligodeoxyribonucleotides containing a high guanine content have a tendency to form intra- or intermolecular complexes in solution make HPLC purification difficult or sometimes impossible. We have developed a simple method that has enabled us to purify a series of highly guanine-rich and s