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Novel polymorphisms in the upstream region of the human dopamine D4 receptor (DRD4) gene

✍ Scribed by Hiroshi Mitsuyasu; Hidetoshi Ozawa; Yasuhiko Takeda; Yasuyuki Fukumaki


Publisher
Nature Publishing Group
Year
1999
Tongue
English
Weight
102 KB
Volume
44
Category
Article
ISSN
1435-232X

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The dopamine D4 receptor (DRD4) is a member of the D2-like dopamine receptor family. Polymorphisms at the DRD4 gene have been examined for association with a wide range of neuropsychiatric disorders and normal behavioral variation. The DRD4 gene is unusual in its high amount of expressed polymorphis

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The term genomic imprinting has been used to refer to the differential expression of genetic material depending on whether it has come from the male or female parent. In humans, the chromosomal region llp15.5 has been shown to contain 2 imprinted genes (H19 and IGF2). The gene for the dopamine D4 re