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Association analysis of polymorphisms in the upstream region of the human dopamine D4 receptor gene (DRD4) with schizophrenia and personality traits

✍ Scribed by H. Mitsuyasu; N. Hirata; Y. Sakai; H. Shibata; Y. Takeda; H. Ninomiya; H. Kawasaki; N. Tashiro; Y. Fukumaki

Publisher
Nature Publishing Group
Year
2001
Tongue
English
Weight
73 KB
Volume
46
Category
Article
ISSN
1435-232X

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## Abstract We have examined the hypothesis that a variable number of tandem repeats in the third cytoplasmic loop of the dopamine D4 receptor influences clinical response to clozapine using a sample of 189 schizophrenic patients. Alleles of the 48‐bp repeat, which range from two to ten copies in t