✦ LIBER ✦

Novel adenosine A1 receptor antagonists. Synthesis and structure–activity relationships of a novel series of 3-(2-cyclohexenyl-3-oxo-2,3-dihydropyridazin-6-yl)-2-phenylpyrazolo[1,5-a]pyridines

✍ Scribed by Satoru Kuroda; Atsushi Akahane; Hiromichi Itani; Shintaro Nishimura; Kieran Durkin; Yoshiyuki Tenda; Kazuo Sakane

Book ID: 108480780
Publisher: Elsevier Science
Year: 2000
Tongue: English
Weight: 251 KB
Volume: 8
Category: Article
ISSN: 0968-0896
DOI: 10.1016/s0968-0896(99)00258-8

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Discovery of 6-Oxo-3-(2-phenylpyrazolo[1

Discovery of 6-Oxo-3-(2-phenylpyrazolo[1,5-a]pyridin-3-yl)-1(6H)-pyridazinebutanoic Acid (FK 838): A Novel Non-Xanthine Adenosine A1 Receptor Antagonist with Potent Diuretic Activity

✍ Akahane, Atsushi; Katayama, Hirohito; Mitsunaga, Takafumi; Kato, Takeshi; Kinosh 📂 Article 📅 1999 🏛 American Chemical Society 🌐 English ⚖ 75 KB

Structure activity relationships of a se

Structure activity relationships of a series of 3-(1,2,5,6-tetrahydropyridin-3-yl)indoles at 5-hydroxytryptamine1A and 5-hydroxytryptamine2 receptor subtypes

✍ D.L. Nelson; L.J. Cornfield; G. Lambert; T. Dahlgren; Y. Yang; A.R. Martin 📂 Article 📅 1990 🏛 Elsevier Science 🌐 English ⚖ 230 KB

Discovery of 2-(2-Oxo-1-phenyl-5-pyridin

Discovery of 2-(2-Oxo-1-phenyl-5-pyridin-2-yl-1,2-dihydropyridin-3-yl)benzonitrile (Perampanel): A Novel, Noncompetitive α-Amino-3-hydroxy-5-methyl-4-isoxazolepropanoic Acid (AMPA) Receptor Antagonist

✍ Hibi, Shigeki; Ueno, Koshi; Nagato, Satoshi; Kawano, Koki; Ito, Koichi; Norimine 📂 Article 📅 2012 🏛 American Chemical Society 🌐 English ⚖ 835 KB

Synthesis and Antibacterial Evaluation o

Synthesis and Antibacterial Evaluation of a Novel Series of 2-(1,2-Dihydro-3-oxo-3H-pyrazol-2-yl)benzothiazoles

✍ Alessandro Stella; Kenneth Segers; Steven De Jonghe; Bart Vanderhoydonck; Jef Ro 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 206 KB 👁 2 views

The 2-(1,2-dihydro-3-oxo-3H-pyrazol-2-yl)benzothiazole scaffold was selected as a central core structure for the discovery of novel antibacterial compounds. A systematic variation of the substituents on the oxo-pyrazole moiety, as well as on the benzo moiety, led to the creation of a small and focus

3-(2,5-Dioxopyrrolidin-1-yl), 3-(2,6-dio

3-(2,5-Dioxopyrrolidin-1-yl), 3-(2,6-dioxopiperidin-1-yl), and 3-(1,3-dioxoisoindolin-2-yl)rhodanines. a novel type of rhodanine derivatives

✍ Wolfgang Hanefeld; Martin Schlitzer; Norbert Debski; Helmut Euler 📂 Article 📅 1996 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 286 KB

Synthesis and antibacterial activity of

Synthesis and antibacterial activity of novel series of 2-(p-tolyloxy)-3-(5-(pyridin-4-yl)-1,3,4-oxadiazol-2-yl)quinoline

✍ Ratnadeep S. Joshi; Priyanka G. Mandhane; Wajid Khan; Charansingh H. Gill 📂 Article 📅 2011 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 140 KB 👁 1 views

## Abstract A new series of 2‐(__p__‐tolyloxy)‐3‐(5‐(pyridin‐4‐yl)‐1,3,4‐oxadiazol‐2‐yl)quinoline were synthesized from oxidative cyclization of __N__′‐((2‐(__p__‐tolyloxy)quinoline‐3‐yl)methylene)isonicotinohydrazide in DMSO/I~2~ at reflux condition for 3–4 h. The structures of the new compounds w