## Two procedures are described f o r the two s t e p synthesis o f I 3f-14c_] mevalonolactone and H-methyl mevalonolactone from radioactive methyl magnesium iodide. The f i r s t route involves the addition of radiolabeled methyl mgnesiwn iodide with 1-12,4,10 t r i o x a adamantyl) 4 -t r i t y
Nouvelles Syntheses du Chloropractolol: Marquage au 14C, 2H, 3H
✍ Scribed by Jean-François Pilichowski; Denise Godeneche
- Publisher
- John Wiley and Sons
- Year
- 1979
- Tongue
- French
- Weight
- 447 KB
- Volume
- 16
- Category
- Article
- ISSN
- 0022-2135
No coin nor oath required. For personal study only.
✦ Synopsis
The exchange reaction between benzoyl chlorideand
The reagent thus prepared reacted with 1--(4-aminophenoxy) ,3-isopropylamino, 2-propanol to give chloropractolol (Specific ac-chloracetic acide produced 1 14C -chloracetic chloride in good yield.
📜 SIMILAR VOLUMES
N N , di-2 chloroethyl 4-amino 2-methyl 1-methoxy naphtalen i s labelled with C on two different positions. -uniformly on the four carbons of the dichloroethyl group by means of radioactive ethylene oxide. -o n the carbon of the methoxy group by means of radioactive methyl iodide. ## 14 RESUME L
## Abstract Tritium and ^14^C‐labeled isomers of ethyl acetate are excellent substrates for competitive dual‐labeled radioactive isotopic measurements of β‐deuterium and β‐tritium isotope effects. Methods are given for preparation of the ethyl esters of acetic acid‐2‐^3^H, acetic acid‐2‐^14^C, and
## Abstract In support of a program to develop a treatment for depression, three isotopically labeled forms of the 5‐HT~1B~ antagonist AZ12320927 were synthesized. A tritium labeled version was synthesized for autoradiography using Ir‐catalyzed hydrogen–tritium exchange. A C‐14 labeled version was
## Abstract {0‐methyl ^14^C} and {0‐methyl ^3^H} bergaptene were prepared by methylation of bergaptol with {^14^C} methyl iodide and {^3^H} methyl iodide in radioactive yields respectively 77 % and 59 %. {^14^C} methyl iodide and 11‐hydroxy ibogamine gave {0‐methyl C} tabernanthine with a 60 % radi
## Abstract 4,4‐dimethyl‐1‐(3‐4‐methylenedioxyphenyl)‐1‐pentene‐3‐ol or stiripentol was labelled by ^14^C and ^3^H. ^14^C labelling was performed on the carbone 1 of the pentene group via a four steps procedure after the carbonatation. The radiochemical yield calculated from the precursor (Ba^14^C