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Notes- The Preparation of C 14 -Labeled Spermine and C 14 -Labeled Spermidine

โœ Scribed by Jackson, E; Rosenthal, S


Book ID
126072154
Publisher
American Chemical Society
Year
1960
Tongue
English
Weight
276 KB
Volume
25
Category
Article
ISSN
0022-3263

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The preparation of 14C-labeled FK-506
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## Abstract Utilizing sodium [1โˆ’^14^C]propionate as a precursor, [^14^C]FKโ€506, labeled at carbon atoms 10, 16, 18, 21a, 24, and 26, was produced by fermentative biosynthesis. Extractive isolation followed by chromatographic purification provided material of purity suitable for metabolism studies.