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Notes- Synthesis of L-Valyl-L-tryosyl-L-tyrosyl-Lisoleucyl-L-histidyl-L-prolyl-L-phenylalanine Methyl Ester Dihydrochloride

✍ Scribed by Walton, Edward; Rodin, John; Stammer, Charles; Holly, Frederick


Book ID
126002426
Publisher
American Chemical Society
Year
1961
Tongue
English
Weight
271 KB
Volume
26
Category
Article
ISSN
0022-3263

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Synthese eines hochwirksamen Hypertensin
✍ W. Rittel; B. Iselin; H. Kappeler; B. Riniker; R. Schwyzer 📂 Article 📅 1957 🏛 John Wiley and Sons 🌐 German ⚖ 788 KB

## Abstract The synthesis of Ileu^5^‐hypertensin II‐Asp‐β‐amide, L‐Asparaginyl‐L‐arginyl‐L‐valyl‐L‐tyrosyl‐L‐isoleucyl‐L‐histidyl‐L‐prolyl‐L‐phenylalanine, is described. The highly purified octapeptide is 5 to 10 times as active as noradrenaline on the blood pressure of the rat in the experimental