Several pieces of evidence implicate serotonin receptors in the aetiology of schizophrenia, and recently a number of studies have reported a genetic association between the 102T/C polymorphism of serotonin receptor type 2A gene and schizophrenia. Unfortunately a number of failures to replicate these
No evidence for association of the T102C polymorphism in the serotonin type 2A receptor with suicidal behavior in schizophrenia
β Scribed by Tan, E.C. ;Chong, S.A. ;Chan, A.O.M. ;Tan, C.H.
- Publisher
- John Wiley and Sons
- Year
- 2002
- Tongue
- English
- Weight
- 46 KB
- Volume
- 114
- Category
- Article
- ISSN
- 0148-7299
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Recent findings of an association between schizophrenia and a T102C polymorphism at the 5-HT 2a receptor gene (particularly with genotype 1-2 and 2-2 and allele 2) prompted us to investigate this marker in familial Irish schizophrenic patients, their relatives, and ethnically matched unrelated contr
## Abstract The serotonin 2A (__5βHT2A__) receptor gene has been implicated in the pathogenesis of suicidal behavior by a genetic association between the 5βHT2A C102T silent polymorphism and suicidality in patients with major depression. However, a recent metaβanalysis failed to confirm this associ