The 5-HT2Areceptor gene 102T/C polymorphism is associated with suicidal behavior in depressed patients
✍ Scribed by Arias, Bárbara ;Gastó, Cristobal ;Catalán, Rosa ;Gutiérrez, Blanca ;Pintor, Luis ;Fañanás, Lourdes
- Publisher
- John Wiley and Sons
- Year
- 2001
- Tongue
- English
- Weight
- 77 KB
- Volume
- 105
- Category
- Article
- ISSN
- 0148-7299
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Recent findings of an association between schizophrenia and a T102C polymorphism at the 5-HT 2a receptor gene (particularly with genotype 1-2 and 2-2 and allele 2) prompted us to investigate this marker in familial Irish schizophrenic patients, their relatives, and ethnically matched unrelated contr
## Abstract The serotonin 2A (__5‐HT2A__) receptor gene has been implicated in the pathogenesis of suicidal behavior by a genetic association between the 5‐HT2A C102T silent polymorphism and suicidality in patients with major depression. However, a recent meta‐analysis failed to confirm this associ