Several pieces of evidence implicate serotonin receptors in the aetiology of schizophrenia, and recently a number of studies have reported a genetic association between the 102T/C polymorphism of serotonin receptor type 2A gene and schizophrenia. Unfortunately a number of failures to replicate these
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102T/C SNP in the 5-hydroxytryptamine receptor 2A (HTR2A) gene and schizophrenia in two southern han chinese populations: Lack of association
β Scribed by Zhang, Xian-Ning ;Jiang, San-Duo ;He, Xin-Hui ;Zhang, Li-Na
- Publisher
- John Wiley and Sons
- Year
- 2004
- Tongue
- English
- Weight
- 52 KB
- Volume
- 126B
- Category
- Article
- ISSN
- 0148-7299
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## Abstract The serotonin 2A (__5βHT2A__) receptor gene has been implicated in the pathogenesis of suicidal behavior by a genetic association between the 5βHT2A C102T silent polymorphism and suicidality in patients with major depression. However, a recent metaβanalysis failed to confirm this associ