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No association between an intronic presenilin-1 gene polymorphism and schizophrenia in a Chinese population

โœ Scribed by Hsien-Jane Chiu; Shih-Jen Tsai; Jen-Yeu Chen; Chih-Yuan Lin; Ya-Mei Bai; Hsiu-Li Song; Hao-Che Lai; Chen-Jee Hong

Book ID
117334779
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
66 KB
Volume
87
Category
Article
ISSN
0165-1781

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Mutations in the Presenilin 1 (PS1) gene on chromosome 14 cause most early-onset familial Alzheimer's disease (AD). An intronic polymorphism in the PS1 gene was recently identified and reported to be associated with late-onset AD [Wragg et al., Lancet 347: 509-512, 1996]. The authors found an excess