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NMR assignment of diastereotopic protons in amphetamine by the use of Eu(fod)3

โœ Scribed by G.E. Wright

Publisher
Elsevier Science
Year
1973
Tongue
French
Weight
98 KB
Volume
14
Category
Article
ISSN
0040-4039

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โœฆ Synopsis

In the ABX nmr spectra of amphetamines and related compounds, a problem arises in the assignment of individual A and B protons since usually there is no a priori reason to assign one "quartet" to one or the other of the diastereotopic protons.

(Suggestions have been made, however, that the A proton in (R)-amphetamines, as labelled in structures I and II, corresponds to the upfield signal in the nmr spectra of amphetamine hydrochlorides in deuterochloroform'.

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