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Niphatoxin A and B; two new ichthyo- and cytotoxic tripyridine alkaloids from a marine sponge

✍ Scribed by Ravit Talpir; Amira Rudi; Micha Ilan; Yoel Kashman


Book ID
104216072
Publisher
Elsevier Science
Year
1992
Tongue
French
Weight
135 KB
Volume
33
Category
Article
ISSN
0040-4039

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✦ Synopsis


Two novel cytotoxic tripyridine alkaloids, niphatoxin A & B, have been isolated from the Red Sea sponge Niohate2 a and the structures elucidated on the basis of spectroscopic data.


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Jaspines A and B: two new cytotoxic sphi
✍ VΓ©ronique Ledroit; CΓ©cile Debitus; Catherine Lavaud; Georges Massiot πŸ“‚ Article πŸ“… 2003 πŸ› Elsevier Science 🌐 French βš– 125 KB

The ethanolic extract of the sponge Jaspis sp. collected in Vanuatu showed cytotoxicity against KB tumour cells (IC 95 =10 mg/ml). A bioassay-guided fractionation led to the isolation of two new cytotoxic sphingosine derivatives, jaspine A and jaspine B. Structures were elucidated by spectroscopic m