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Haliclonacyclamines A and B, cytotoxic alkaloids from the tropical marine sponge Haliclona sp

โœ Scribed by Romila D. Charan; Mary J. Garson; Ian M. Brereton; Anthony C. Willis; John N.A. Hooper


Publisher
Elsevier Science
Year
1996
Tongue
French
Weight
572 KB
Volume
52
Category
Article
ISSN
0040-4020

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๐Ÿ“œ SIMILAR VOLUMES


The haliclonacyclamines, cytotoxic terti
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2D-NMR spectroscopic data is reported for the haliclonacyclamines A -D (1)-( ) and for two bismethiodide adducts ($) and ( ). The structures of two new alkaloids, halicionacyclamines C (3) and D (4), which are the 15,16-dihydro analogues of the haliclonacyclamines A (1) and B (2) are described. Revi

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Halitulin (2), a novel bisquinolinylpyrrole has been isolated from the sponge Haliclona tulearensis. Its structure was elucidated mainly on the basis of spectroscopic data as well as chemical modifications. Halitulin was found to be cytotoxic against several tumor cells: P-388, A-549, HT-29 and MEL-