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Halitulin, a new cytotoxic alkaloid from the marine sponge Haliclona tulearensis

โœ Scribed by Yoel Kashman; Ganit Koren-Goldshlager; M.D.Garcia Gravalos; Michael Schleyer

Publisher
Elsevier Science
Year
1999
Tongue
French
Weight
257 KB
Volume
40
Category
Article
ISSN
0040-4039

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โœฆ Synopsis

Halitulin (2), a novel bisquinolinylpyrrole has been isolated from the sponge Haliclona tulearensis. Its structure was elucidated mainly on the basis of spectroscopic data as well as chemical modifications. Halitulin was found to be cytotoxic against several tumor cells: P-388, A-549, HT-29 and MEL-28 in concentrations of 12-25 ng/ml.

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