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Haligramides A and B, Two New Cytotoxic Hexapeptides from the Marine Sponge Haliclona nigra

โœ Scribed by Rashid, Mohammad A.; Gustafson, Kirk R.; Boswell, Jamie L.; Boyd, Michael R.


Book ID
125985662
Publisher
American Chemical Society
Year
2000
Tongue
English
Weight
108 KB
Volume
63
Category
Article
ISSN
0163-3864

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Halitulin, a new cytotoxic alkaloid from
โœ Yoel Kashman; Ganit Koren-Goldshlager; M.D.Garcia Gravalos; Michael Schleyer ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 257 KB

Halitulin (2), a novel bisquinolinylpyrrole has been isolated from the sponge Haliclona tulearensis. Its structure was elucidated mainly on the basis of spectroscopic data as well as chemical modifications. Halitulin was found to be cytotoxic against several tumor cells: P-388, A-549, HT-29 and MEL-