Salicylihalamides A and B, Novel Cytotoxic Macrolides from the Marine Sponge Haliclona sp.
β Scribed by Erickson, Karen L.; Beutler, John A.; Cardellina, John H.; Boyd, Michael R.
- Book ID
- 120170762
- Publisher
- American Chemical Society
- Year
- 1997
- Tongue
- English
- Weight
- 176 KB
- Volume
- 62
- Category
- Article
- ISSN
- 0022-3263
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π SIMILAR VOLUMES
Following the characterization of callipeltoside A (1), the first member of a novel class of marine glycoside macrolides, two more bioactive constituents, callipeltoside B (2) and C(3), were isolated from Callipelta sp. in very low amounts. The structures, assigned on the basis of spectral analysis,
2D-NMR spectroscopic data is reported for the haliclonacyclamines A -D (1)-( ) and for two bismethiodide adducts ($) and ( ). The structures of two new alkaloids, halicionacyclamines C (3) and D (4), which are the 15,16-dihydro analogues of the haliclonacyclamines A (1) and B (2) are described. Revi