𝔖 Bobbio Scriptorium
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Callipeltosides B and C, two novel cytotoxic glycoside macrolides from a marine lithistida sponge Callipelta sp.

✍ Scribed by Angela Zampella; M.Valeria D'Auria; Luigi Minale; Cécile Debitus

Publisher
Elsevier Science
Year
1997
Tongue
French
Weight
316 KB
Volume
53
Category
Article
ISSN
0040-4020

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✦ Synopsis

Following the characterization of callipeltoside A (1), the first member of a novel class of marine glycoside macrolides, two more bioactive constituents, callipeltoside B (2) and C(3), were isolated from Callipelta sp. in very low amounts. The structures, assigned on the basis of spectral analysis, include the same 14-membered macrolide as in callipeltoside A (1) but differed in the saccharide moieties.

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Jaspines A and B: two new cytotoxic sphi
Jaspines A and B: two new cytotoxic sphingosine derivatives from the marine sponge Jaspis sp.
✍ Véronique Ledroit; Cécile Debitus; Catherine Lavaud; Georges Massiot 📂 Article 📅 2003 🏛 Elsevier Science 🌐 French ⚖ 125 KB

The ethanolic extract of the sponge Jaspis sp. collected in Vanuatu showed cytotoxicity against KB tumour cells (IC 95 =10 mg/ml). A bioassay-guided fractionation led to the isolation of two new cytotoxic sphingosine derivatives, jaspine A and jaspine B. Structures were elucidated by spectroscopic m