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New synthesis of pipecolic acid and analogs

✍ Scribed by Vikram Asher; Christian Becu; Marc J.O. Anteunis; Roland Callens

Publisher
Elsevier Science
Year
1981
Tongue
French
Weight
171 KB
Volume
22
Category
Article
ISSN
0040-4039

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A new general method for the preparation of 2-alkyl-pipecolic acids has been developed. The syntheses of 2-methyl-, 2-benzyl-and cis-6-methylpipecolic acids are described. (-)S-and (+)R-2-methylpipecolic acids were resolved by fractional crystallization of the quinine salt of their N-carbobenzoxy de