The first total synthesis of (+)-perhydrohistrionicotoxin (I), a useful neurotoxin, 1 was recently reported from these Laboratories. 2,3 We now describe a new, efficient and stereocontrolled route which leads to (t)-perhydrohistrionicotoxin
β¦ LIBER β¦
New routes to perhydrohistrionicotoxin
β Scribed by David Tanner; Peter Somfai
- Book ID
- 108371933
- Publisher
- Elsevier Science
- Year
- 1986
- Tongue
- French
- Weight
- 641 KB
- Volume
- 42
- Category
- Article
- ISSN
- 0040-4020
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
A new synthetic route to (Β±)-perhydrohis
β
E.J. Corey; Martin Petrzilka; Yoichiro Ueda
π
Article
π
1975
π
Elsevier Science
π
French
β 265 KB
A New Synthetic Route to (Β±)-Perhydrohis
β
E. J. Corey; Martin Petrzilka; Yoichiro Ueda
π
Article
π
1977
π
John Wiley and Sons
π
German
β 604 KB
## Abstract Starting from ethyl 2βcyclohexenβ1βcarboxylate (**3**) the total synthesis of the perhydrohistrionicotoxin intermediate **23** was achieved in 25% overallβyield. The two key steps involve a positionally specific addition of HOBr to the oximeβolefin **7** and the alkylation of bromooxime
A new stereoselective synthetic route to
β
Toshiro Ibuka; Yoshinori Mitsui; Kenji Hayashi; Hiroyuki Minakata; Yasuo Inubush
π
Article
π
1981
π
Elsevier Science
π
French
β 240 KB
A stereoselective organopalladium route
β
Tanner, David; Sellen, Mikael; Baeckvall, Jan E.
π
Article
π
1989
π
American Chemical Society
π
English
β 772 KB
Formal total synthesis of perhydrohistri
β
Godleski, Stephen A.; Heacock, Deborah J.; Meinhart, James D.; Van Wallendael, S
π
Article
π
1983
π
American Chemical Society
π
English
β 470 KB
New routes to antimalarials?
β
Barton, Samantha
π
Article
π
2006
π
Nature Publishing Group
π
English
β 107 KB