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A stereoselective organopalladium route toward perhydrohistrionicotoxin

✍ Scribed by Tanner, David; Sellen, Mikael; Baeckvall, Jan E.

Book ID
127353242
Publisher
American Chemical Society
Year
1989
Tongue
English
Weight
772 KB
Volume
54
Category
Article
ISSN
0022-3263

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πŸ“œ SIMILAR VOLUMES

A new synthetic route to (Β±)-perhydrohis
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✍ E. J. Corey; Martin Petrzilka; Yoichiro Ueda πŸ“‚ Article πŸ“… 1977 πŸ› John Wiley and Sons 🌐 German βš– 604 KB

## Abstract Starting from ethyl 2‐cyclohexen‐1‐carboxylate (**3**) the total synthesis of the perhydrohistrionicotoxin intermediate **23** was achieved in 25% overall‐yield. The two key steps involve a positionally specific addition of HOBr to the oxime‐olefin **7** and the alkylation of bromooxime